- Solutions for Challenges in Extraction and Quantitation of Arsenic in Food
- June 1, 2017
Along with rice and apple juice, seafood and seaweed are major sources of human exposure to dietary arsenic. Although toxic inorganic chemical forms of arsenic such as arsenate or arsenite are well understood, the safety and toxicity of arsenosugars and lipid-soluble arsenicals are still under debate. The literature is limited in terms of the methods and sample groups used for such analyses, but the range and variation of arsenic in each species affect its characterization and quantitation.
- Simultaneous Determination of 24 Veterinary Drugs by UPLC-MS/MS
- April 1, 2016
A UPLC-MS/MS-based method was developed and validated for the simultaneous confirmation and quantification of 24 analytes of quinolones, including fluoroquinolones, sulfonamides and tetracyclines and its epimers following the European Union’s (EU) performance criteria (CD 2002/657/EC). Samples were extracted using a simple method by acidified acetonitrile (0.5 mL of 0.1% formic acid in 7 mL acetonitrile) with a clean-up step using n-hexane and methanol, followed by ultra-performance liquid chromatography-electrospray-tandem mass spectrometry (UPLC-ESI-MS/MS). The method validation and proficiency testing provided evidence that the method is suitable for the detection and quantification of 24 antibiotic residues in routine analysis of fish and fishery products.